Sentence examples for major cell classes from inspiring English sources

The mammalian retina is composed of seven major cell classes, with intrinsic cues being sufficient for specification of the majority of cell types (Cayouette et al., 2003; Cepko, 1999; Hatakeyama and Kageyama, 2004; Livesey and Cepko, 2001).

The seven major cell classes of the vertebrate retina are organized with remarkable precision into distinct layers.

The retina of vertebrates is remarkably conserved during evolution, both in terms of major cell classes and laminar anatomical organization.

All vertebrate retinas share a fundamental plan, comprising five major neuronal cell classes with cell body distributions and connectivity arranged in stereotypic patterns.

The possibility that it is a technical artifact of the analysis must be considered, but it also dominates the profiles of only the individuals with the highest quality RNA (see methods), it is hard to conceive that an artifact would stably transmit across the generations, and would so clearly correlate with a measure of differentiation of major T cell classes.

In this study, we show that each of the three major PV cell classes further splits into functionally distinct sub-classes during fast network events in vivo.

Here, we cultured three major neural cell classes of rat brain (ie, neurons, astrocytes, and oligodendrocyte precursor cells [OPCs]) obtained from commercial sources.

DOI: http://dx.doi.org/10.7554/eLife.04006.010 In terms of fast rhythms, our results revealed clear distinctions between the three major PV cell classes.

Importantly, in addition to inter-class differences between PV cells, our data also revealed that robust intra-class distinctions emerged from all three major PV cell classes during fast (>90 Hz), but not slow, network oscillations.

We have included a new summary figure that highlights the key findings about the temporal sequences of phase-preferential firing by the three major PV cell classes and the ripple-related discharge patterns of the newly described PV interneuron subclasses.

Taken together, these data show that the firing of PV interneurons segregates according to the three established major PV cell classes during epsilon oscillations that take place when the animal is running.