Sentence examples for major cell adhesion from inspiring English sources

Vitronectin is a major cell adhesion glycoprotein that is found in plasma and the extracellular matrix.

Therefore, we analyzed the localization of ezrin, a protein that is restricted to the apical cortex of outer cells [24] and E-cadherin, the major cell adhesion molecule involved in intercellular flattening in the preimplantation embryo [25], as markers of the apical and basolateral domains, respectively, in compacted 8-cell stage embryos.

Furthermore, another major cell adhesion molecular family is the immunoglobulin superfamily (PF00047).

As a family of major cell adhesion receptors, integrins uniquely combine bidirectional signaling capabilities with the structural functions of linking extracellular matrix proteins to the cytoskeleton.

CD44 is a major cell adhesion molecule that participates in various physiological events, including lymphocyte homing, wound healing, and cell migration as well as in cancer cell growth and metastasis [ 30].

The major cell adhesion molecules at AJs, the classical cadherins, connect adjacent cells through homophilic interactions and are linked to the cytoskeleton through proteins associated with their cytoplasmic tail, the catenins.

Also PYK2, a major cell adhesion-activated tyrosine kinase interacts with MyD88 and appeared to be tyrosine phosphorylated upon coexpression of PYK2 and regulates MyD88-mediated NF-kB activation in macrophages [40].

The nonreceptor tyrosine kinase Pyk2, a major cell adhesion-activated tyrosine kinase in osteoclasts, was activated by RANKL, which was suppressed by ≥10  μM phloretin).

As the majority of these frameshift and nonsense mutations is predicted to generate secreted E-cadherin fragments, the functionality of this major cell-cell adhesion protein is lost.

Proximal tubular cells are the only epithelial cells in the human adult organism which express N-cadherin instead of E-cadherin as major cell-cell adhesion protein, which allows differentiation of cells of proximal and distal origin by immunocytochemistry [ 18, 19].

The individual GO terms affected three major fields: cell adhesion, apoptosis/development, and (lipid) metabolism.