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The company did make at least one major breakthrough, however, when it splashed out $1.65bn to purchase YouTube in October.
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However, major breakthrough still not been made in the clastic stratigraphic reservoir exploration of northwestern margin of Junggar Basin since 2005.
However, a major breakthrough in diabetes modeling occurred with the development of the physiological model for glucose disappearance following IVGTT.
However, the major breakthrough came with the important series of investigations by Walther van Venrooij and colleagues, who discovered the crucial role of post-translationally citrullinated peptide epitopes and developed the anti-CCP test.
However, a major breakthrough in the CSI of NRRL1951 was the selection of the so-called Wisconsin series of improved strains that were derived from the X-1612 (implying X-ray treatment) mutant that was further evolved into the current international laboratory standard strain Wisconsin 54-1255 whose genome sequence became available in 2008 [ 2].
This would depend, however, on a major breakthrough in public consciousness, something theoretically possible for which there is little evidence at present.
Technical limitations in large-scale crystallization screens have, however, prevented a major breakthrough in the routine application of this technology.
However, recently a major breakthrough has been realized which will bring SHARED very rapidly into the famous "log phase of growth" for networks.
The repercussions these observations have in the clinical context however might suppose a major breakthrough and therefore well worth the effort in pursuing.
However, up to now, a major breakthrough in finding a substance that selectively enhances glucose uptake could not be achieved in pharmaceutical research.
The question of whether PTIME can be characterized by a logic of the form FO* Q) remains open, however (indeed, solving it would be a major breakthrough in complexity theory).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com