Sentence examples for major breakdown in from inspiring English sources

We haven't had a major breakdown in security".

Her therapist has died, and she has just suffered a major breakdown in a Disney store.

By then, having suffered a major breakdown in 2007, Duffy was resigned to retirement.

The first major breakdown in the Roman imperial system came in 166 CE, and further crises followed until the Western empire ceased to exist in 476 CE.

"And as a result, we have 20,000 voters being disenfranchised, and we think that is a major, major breakdown in the electoral process".

Redundancy is key: a major breakdown in that tunnel could deal a blow not only to many thousands of commuters and other passengers but the regional economy as a whole.

The first is technicals after major breakdowns in the prices of key raw materials iron and copper, both barometers of global growth.

Massive releases of methane into the atmosphere mean that climate turbulence is going to radically escalate and do so increasingly destructively, causing major breakdowns in our economic and social order.

The major breakdown product in vitro was identified as EO-5A which proved relatively inactive compared to EO-9 (IC50 = 50 and 0.6 ug ml-1 respectively).

According to California Watch, the non-profit investigative organization that issued the report, a review of tens of thousands of pages of documents revealed that a major breakdown had occurred in the state regulatory system designed to ensure that California's school buildings remain safe in the event of an earthquake.

However, both scFvE2/p17 and scFvG2/p17 proteins were stable over a period of 72 h, with no major breakdown products detected in the Western blot patterns.