Sentence examples for major bottleneck which from inspiring English sources

This makes disk access a major bottleneck which significantly degrades the performance.

On the way from DNA to product translation is a major bottleneck which may limit the specific productivity of mammalian production cell lines.

The proposed approach, while yielding significant potential, suffers from a major bottleneck, which is the amount of resources (chiefly biomodeler time) required to build knowledge-based multiscale models of diseases.

Poor rate capability and cycling stability are the major bottlenecks which hinder the application of polypyrrole (PPy) as the supercapacitor electrode material.

Secretion engineering, illustrated here by Xbp1-based reprogramming of the post-translational processing machinery, provides a first insight into mastering a major system bottleneck which impacts biopharmaceutical manufacturing of secreted protein therapeutics.

This bypass successfully eased the flow of traffic away from the main shopping street, but the joining of three major roads remains a bottleneck, which will be eased by a proposed eastern bypass.

We identify a mismatch between the size of the S6s reconfigurable fabric and the available interface bandwidth as the major bottleneck limiting performance which makes it a poor choice for scientific workloads relying on native support for floating-point arithmetic.

However, the availability of tools and reagents is a major bottleneck in the biomarker pipeline, which has consequences for the development of disease-modifying osteoarthritis drugs (DMOADs).

Most of the epitope prediction models are based on HLA-II peptide binding, which constitutes a major bottleneck in the natural selection of epitopes.

Despite efforts to speed it up, it remains a major bottleneck in the handling of data, which must travel back and forth between the memory and bus during the computing process.

Precisely reprogrammed cells with fewer factors should have better clinical prospects and also could facilitate the achievement of homogenous insulin producing cells, which is a major bottleneck that hampers the clinical translation of artificially reprogrammed cells.