Sentence examples for major bone cells from inspiring English sources

A significant body of evidence has been published over the last 10 years indicating that all major bone cells have the capacity to metabolise 25-hydroxyvitamin D (25(OH)D3) to 1,25(OH)2D3, which in turn exerts autocrine/paracrine actions to regulate bone cell proliferation and maturation as well as bone mineralisation and resorption.

There are, indeed, four major bone cell types, and each of them seems to be influenced by μg.

Osteoclasts are the major bone resorbing cells.

All the in vivo results obtained in space point to major alterations of bone cells.

Osteocytes, the major type of bone cells which reside in their lacunar and canalicular system within the bone matrix, function as biomechanosensors and biomechanotransducers of the bone.

Bone cells exert major effects on the immune system.

OPN, rather than HA, is the major ligand for CD44 on bone cells in the remodelling phase of healing of fractures [ 216].

Parathyroid hormone-related protein is a major mediator between tumour and bone cells and induces the osteolytic process through the RANKL pathway (Guise, 2000).

In addition to these direct effects on bone cells, the major action of estrogens in vivo is believed to be mostly by indirect actions, regulation of growth factors and cytokines in osteoblasts, which in turn regulate osteoclast differentiation and activation [ 2].

Similarly, high degree of overall molecular homogeneity in gene expression was seen between symmetrical sites in ILC [20] underscoring the importance of function as a major determinant of bone cell gene expression.and adaptability.

A major breakthrough in bone cell biology was the identification of receptor activator of NF-κB ligand (RANKL), the stem cell factor for osteoclasts [ 2, 3].