Sentence examples for major bleeding risk from inspiring English sources

There were no signals with respect to increased cardiovascular morbidity or major bleeding risk.

To address this evidence gap, we conducted a case control study to evaluate the association between BMI and major bleeding risk among patients receiving warfarin.

Actually, in trials considering the elderly population, OAT was associated with significant reduction in thromboembolism occurrence, as well as lower major bleeding risk.

All other patients - those at 'high' risk on the Beyth Outpatient Bleeding Risk Index (due to their high estimated major bleeding risk, or with additional risk factors, as detailed above), will be mandated to receive the Level 2 Service.

Bivalirudin was associated with lower major bleeding risk compared with unfractionated heparin plus GpIIb/IIIa inhibitor (relative risk 0.47 (0.30 to 0.74)) or unfractionated heparin (0.58 (0.37 to 0.90)).

In a meta-analysis of the impact of impaired renal function on bleeding in patients receiving another form of anticoagulation that is renally excreted the low-molecular-weight heparin, enoxaparin therapeutic doses were associated with an almost fourfold increase in major bleeding risk in those with a CrCl of 30 mL/min or less compared with those with a CrCl >30 mL/min.

23 In contrast, in atrial fibrillation studies, the novel oral anticoagulants were associated with similar risk of major bleeding (relative risk 0.88, 95% confidence interval 0.71 to 1.09).

Patients whose INR strays too far from the optimal level of anticoagulation are at increased risk of experiencing a hemorrhagic or thromboembolic event [ 5], with significantly higher incidence of thromboembolism [relative risk 4.5 for INR <2.0, 95% confidence interval (CI) 3.1 6.6, P < 0.001] or major bleeding (relative risk 6.4 for INR >5.0, 2.5 16.1, P < 0.001) compared with INR 2.0 3.0 [ 6].

Mechanical prophylaxis was only protocolized for use if anticoagulant prophylaxis was contraindicated (major bleeding, high risk for major bleeding, or suspected or proven heparin-associated thrombocytopenia).

Indeed, the intravenous route provides immediate anticoagulation, with rapid clearance, 49 avoiding exposure to prolonged anticoagulation after percutaneous coronary intervention, and in this study was associated with a 34% reduction in major bleeding (absolute risk reduction 1.52%) compared with unfractionated heparin.

In the recent POISE-2 study, it was shown that peri-operative intake of aspirin (100-200 mg daily) increased risk of major bleeding in patients, while risk of death or non-fatal myocardial infarction was not reduced when compared to the placebo group [ 4].