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There was no major bleeding observed during the insertion of the electrodes.
The ability of US to provide this anatomical information may explain the low incidence of serious complications (such as major bleeding) observed in our obese patients.
However, there was an increased risk of major bleeding observed in 2.4% of the patients receiving prasugrel compared with 1.8% of the patients receiving clopidogrel (HR 1.32; P = 0.03).
The main efficacy and safety outcomes (prevention of embolism and major bleeding) observed in the comparison between dabigatran and warfarin are displayed in figure 2 and table 4. The funnel plot to ascertain publication bias is shown in figure 3.
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These sources of heterogeneity are evident in the differences in the minimum and maximum major bleeding rates observed in the RCTs and observational studies.
A decrease in pneumothorax or major bleeding is observed.
No minor or major bleeding was observed, and the placental and fetal examination was always normal.
No major bleeding was observed during surgery after prothrombin complex concentrate administration.
This finding is consistent with the median major bleeding rate observed across our included studies (2.0 per 100 patient-years).
Major bleeding was observed in 0.7% of rivaroxaban-treated patients compared with 0.3% of enoxaparin-treated patients (P = 0.1096).
The TIMI major bleeding was observed in 2.4% of subjects in the prasugrel group and in 1.8% in the clopidogrel group.
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