Sentence examples for major biological pathways from inspiring English sources

Indeed, Mendelian disorders or birth defects resulting from naturally occurring ADAMTS2, ADAMTS3, ADAMTS10, ADAMTS13, ADAMTS17, ADAMTS20, ADAMTSL2 and ADAMTSL4 mutations as well as numerous phenotypes identified in genetically engineered mice have revealed ADAMTS participation in major biological pathways.

From the caloric restriction studies, scientists have started to identify a few major biological pathways — chains of chemical reactions within the body — that likely play a key role in aging.

The consistent expression pattern across all the cancer subgroups may indicate that these genes participate in many major biological pathways involved in cancer formation and progression.

The pathogenesis of DISH from most drugs is complex involving major biological pathways of hepatocyte lipid metabolism.

Supplementary information, Table S1A lists all the genes upregulated or downregulated in major biological pathways by KEGG pathway analysis.

This array consisted of 84 genes representing the major biological pathways involved in tumor progression, as described in Methods.

The major biological pathway capable of triggering such idiosyncratic ADRs is activated by a drug's direct binding with human leukocyte antigen (HLA) protein variants [4 6].

Nearly every major biological pathway in bilateral animals appears to be under the control of miRNAs, including developmental timing, cell differentiation and proliferation, apoptosis, energy metabolism, and antiviral defense.

Moreover, the microarray data generated in this work identified lipid metabolism as the major biological pathway altered in ostes/ ostes skeletal muscle: eight out of the top nine genes upregulated in ostes/ ostes muscle have functions in lipid metabolism (Supplementary Material, Table S2; see also deposited data ArrayExpress, accession number E-MEXP-1873 E-MEXP-1873 E-MEXP-1873

The heatmaps in Figures 6 A and B depict the major altered biological pathways.

In the current study, we present a comprehensive comparison of different similarity-based and machine learning methods in predicting the interference of chemical compounds in two major groups of biological pathways, the nuclear receptor pathway and stress response pathway, using the Tox21 screening data.