Sentence examples for major binding site from inspiring English sources

All NLSs bind to the major binding site, spanning armadillo repeats 1 4, and some also have a small additional contribution from the minor site, spanning repeats 6 8.[ 8] TPX2, however, binds primarily to the minor site of importin-α, thereby offering an opportunity for selectivity.

Studies have shown that the N-terminal "KR" motif of bipartite NLSs binds the P1' and positionsiofs of the minor binding site in importin α, while the larger "KRRK" motif binds the P2 P5 positions of the major binding site in importin α [36] (Fig. 8A).

Although CGG repeats constitute a major binding site for CGGBP1, there are CGG-free regions to which it binds.

The heparin binding domain 3 (HBD-3), also located at the C-terminal end, is the major binding site for most studied bacterial Vn-binding proteins8.

This result suggests that, in contrast to most other known Vn-binding proteins, KatA does not use HBD-3 as a major binding site but may have additional binding region(s).

We found that affinity and avidity adjusted inserted (I) domain, the major binding site of LFA-1, on liposome surface enhanced the specificity toward lipopolysaccharides (LPS -treated or infLPS -treatedelial cells (HMEC-1) and morocytes (THP-1) vinflamed1 ovendothelialn, reflecells inherent affinity and avidity modulation of these molecules in physiology.

The major binding sites on DNA and their binding affinities toward the surfactant (DTAB) are identified by Fourier Transform InfraRed (FTIR) spectroscopy.

For three of the Fab libraries, the CDR regions appeared as major binding sites for all multimodal ligands.

The selectivity displayed by the synthesised model compound 2 towards Cu2 + ions ascertained the participation of pyridine N′s of DPA as the major binding sites.

These efforts will create high-resolution, functional maps of linear and nonlinear epitopes comprising the major binding sites of both isolate-specific and broadly neutralizing antibodies for rational vaccine design.

Carboxylate anion groups are the major binding sites in wool [20] and silk [23].