Sentence examples for major binding region from inspiring English sources

Salbutamol had at least one other major binding region.

The major binding region (from 250 to 350 residues) showed no significant increment in structure of RbAp48 with all ligands.

However, the chain B of the c-Jun has relative fewer frequency of fluctuation and the major binding region (from 228 to 240 residues) showed a less fluctuation as shown in Figure 12(b).

The sequence number of the major binding region was from 250 to 350, and the values for disorder disposition were below 0.5, which indicated that the binding site of RbAp48 is a folded structure, and the ligand binding may not be affected by protein structure [ 46].

Two exclusively lethal regions, helix positions 691-823 and 910-964 aligned with major binding regions [ 20] and we find a positively selected site in this region.

Verapamil is a calcium channel blocking agent, and chlorpromazine is an antipsychotic drug that each have a primary binding site at or near Sudlow site I. Tolbutamide, acetohexamide, and gliclazide are sulfonylurea drugs used to treat type 2 diabetes and have two major binding regions on HSA, which occur at Sudlow sites I and II.

There are two major functional domains, the N-terminal domain (NT), contains the major receptor binding region, the C-terminal domain (CT), contains the lipid binding region, which is also thought to bind Aβ [9], [10].

We confirm that of the two ApoE domains, the ApoE CT is in closer apposition to Aβ, supporting the notion that the C-terminal domain, containing the major lipid binding region is the region that interacts with Aβ, and that the CT of both ApoE3 and ApoE4 interact closely with Aβ.

The C-terminal domain has an α-helical structure and contains the major lipid binding region at residues 244 to 272.

Pull‐down assays using ctPan3 PKC and N‐ or C‐terminal truncations of ctPan2 (Fig  5A and Supplementary Fig S7D and E) suggest that the major Pan3 binding region on ctPan2 includes the segment seen in the crystal structure.

In the present work, we genetically installed an M13 peptide sequence into Loop 12 of kinesin, which is one of the major microtubule binding regions of the protein.