Sentence examples for major basal from inspiring English sources

Substantia nigra pars reticulata (SNr) is a major basal ganglia output area that is a target of these GABAergic projections, and research from animal models has indicated that stimulation of GABA receptors in SNr can produce motor effects consistent with an antiparkinsonian action.

Although the major basal cell-specific integrin ITGA6, encoding hemidesmosomes and relevant to stem/progenitor cell function, was present in both human and mouse airway basal cell signatures (Table S2), the genes encoding integrins ITGA5 and ITGB6 were enriched in human, but not mouse basal cells.

Notably, the major basal cell-specific integrin ITGA6, encoding hemidesmosomes, structures critical for the anchorage of the intermediate and luminal cells to the basal cell layer [64], and relevant to the stem/progenitor cell phenotype of basal cells in tissues such as the breast and skin [65] [67], was present in the human basal cell signature, as it is in mouse [7].

In all analyses, Clitellata is derived from polychaetous ancestors; it does not form a major basal branch of annelids (Figs. 1, 2, Additional files 1, 2, 3, 4).

The various 'relaxed clock' methods all indicate that the major (basal) lineages of modern birds originated deep within the Cretaceous, although temporal intraordinal diversification patterns differ across methods.

Our structural analysis of the basal body reported here has paved the way for identification of major basal body components within the context of a 3D structure.

Additional predicting variables for PA+ patients were the following: for healing, transcutaneous oxygen tension [ΔTcP o2]; and for major amputation, basal TcP o2, basal A1C, ΔTcP o2, and percutaneous angioplasty technical failure.

The myoglobin tree suggests with 0.94 posterior probability that Taraba major is basal to Batara cinerea and Hypoedaleus guttatus, while Taraba major is basal also to Mackenziaena severa and Frederickena unduligera with 0.99 posterior probability in both the combined and the cytochrome b trees.

TNBCs include two major subtypes: basal-like, expressing basal-cell markers such as cytokeratin 14, and claudin-low/mesenchymal-like, expressing low levels of tight junction proteins including certain claudins and E-cadherin, and high levels of genes associated with epithelial-to-mesenchymal transition (EMT) (Prat et al, 2010; Lehmann et al, 2011; Timmerman et al, 2013).

In 2006, Neve et al. [ 19] identified two major groups (basal and luminal) in a panel of ~50 breast cancer cell lines by independently comparing the global expression profiles of cell lines and primary breast tumors.

Even the listed study with the fewest taxa [ 9] was based on exemplar species, compiled by the Green Plant Phylogeny Research Coordination Group and chosen to represent most of the major putatively basal lineages suggested by a large body of previously accumulated results.