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Discover Ludwig"major barrier" is correct and usable in written English.
You can use it to describe something that is a very large obstacle. For example, "Lack of access to healthcare is a major barrier to achieving a healthy lifestyle."
Exact(59)
Cost is the major barrier.
Bureaucracy is one major barrier, explains Hannigan.
"Poverty is a major barrier to women getting treatment".
This is a major barrier to reconciliation," the report says.
Another major barrier is the lack of research.
Investment remains the major barrier to scaling up such technologies.
Finance is a major barrier to reaching the education SDG.
Fatigue is a major barrier to doing anything.
It says "inappropriate and inconvenient opening hours are perceived [by the public] as a major barrier".
Another major barrier in the uptake of sharing economy businesses is the confusion around tax.
CARE International UK has long recognised that this is a major barrier to poverty reduction.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com