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Consecutively, we investigated the protein level of effectors downstream of the major autophagy regulating protein complexes.
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How is constitutive autophagy regulated in healthy neurons?
Hars, E. S. et al. Autophagy regulates ageing in C. elegans.
"Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1". Autophagy 11, no. 12 (January 2015): 2335-2345.
We present data that DENV induction of autophagy regulates cellular lipid metabolism.
Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes.
Autophagy regulates IL-1β secretion through at least two separate mechanisms.
Autophagy regulates innate immunity via inhibition of mitochondrial DNA (mtDNA) release via by the inflammasome.
More recently, it has been shown that autophagy regulates the lysosomal release of lysosomal components by osteoclasts [6], and pharmacological inducers of autophagy reduce pathological osteoclast formation [7].
Importantly, autophagy regulates infection [23].
Autophagy regulates inflammatory signals directly.
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