Sentence examples for major apoptotic pathways from inspiring English sources

There are two major apoptotic pathways: the intrinsic and extrinsic pathway.

This review briefly summarizes the major apoptotic pathways and molecules and presents the most important oral diseases that are related to dysregulation of apoptosis.

However, little is known about the real-time dynamics of even the identified prominent molecular processes involved in the major apoptotic pathways.

Spheroids that were starved but un-stressed had much less apoptosis than those in the compressed samples, again indicating that limitations of glucose, serum and oxygen alone do not account for the levels of cell death demonstrated in Fig. 4. Finally, we investigated which of the two major apoptotic pathways [15] regulates the solid stress-induced cell apoptosis.

Survivin-ΔEx3 provides a link between two major apoptotic pathways.

Two major apoptotic pathways exist: the death receptor and the mitochondrial pathways [ 17].

The mitochondria-mediated caspase activation pathway is a major apoptotic pathway characterized by mitochondrial outer membrane permeabilization (MOMP) and subsequent release of cytochrome c into the cytoplasm to activate caspases.

Second, the mitochondrial pathway is the major apoptotic pathway involved in the nephrotoxicity of cisplatin.

Binding of a death ligand to its receptor activates one major apoptotic pathway.

These experimental results suggest that the mitochondrial pathway is the major apoptotic pathway involved in the nephrotoxicity of cisplatin.

Figure 1 summarises the major apoptotic pathway in mammalian cells and the current recognised sites of interference of COX inhibitors.