Sentence examples for major antigenic differences from inspiring English sources
Furthermore, sequence divergence in VP1 and other external regions of the capsid is actually greater than between different HRV-A or –B serotypes, implying the existence of major antigenic differences that influence immunological cross-protection in this newly discovered species.
Each serotype could be divided into two genetic lineages, but these did not reflect major antigenic differences.
Traditionally, rotaviruses have been classified into (sero groups on the basis of major antigenic differences that predominantly reside in the VP6 and of the genomic RNA profile obtained by polyacrylamide gel electrophoresis and silver staining (1 ).
However, leptospiral LPS is highly variable; its variations are thought to be the major antigenic determinant defining differences between approximately 230 serovars and contributing to serovar specific immunity [7].
Initial qPCR primers and probes have been designed to predict antigenic differences in major outer membrane protein (MOMP) to determine the serovar as previously described [ 27, 36- 38].
Additionally, influenza A is further classified into major subtypes based on genetic and antigenic differences in the membrane glycoproteins hemagglutinin and neuraminidase [7].
Confirmatory assay parameters that contribute to this disagreement include differences in antigen selection (full length LEDGF vs. major antigenic region), recombinant expression system used for antigen production (E. coli vs. Baculo virus system vs. mammalian cells), analytical sensitivity/specificity of the various assay platforms and the established assay cut-off.
Important biological and antigenic differences exist between variants, and different genotypes respond differently to treatment [7].
Here, it has been detected a 38 kDa protein band that corresponded to Amb a 1, the major antigenic component of ragweed pollen, with no quantitative difference between non-fumigated and fumigated pollen grains.
Many bacteria synthesize structurally diverse polysaccharide polymers, O-antigen and capsule that are major antigenic determinants.
YPT is commonly typed serologically according to antigenic differences in the lipopolysaccharide O antigen.
