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Allopurinol supplementation led to a 2-fold reduction in the required antimony dosage and resulted in a cure rate of 75 80% in Iranian patients infected with L. major and improved treatment outcomes for patients treated with a single agent while infected with L. tropica.
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A 2006 systematic review and meta-analysis of 14 randomized trials showed home testing led to a reduced incidence of complications (thrombosis and major bleeding) and improved the time in the therapeutic range.
Simultaneous targeting of LPS, IL-6 and C5a reduced major inflammatory mediators, reversed immunoparalysis and improved major disease severity scores.
Among patients with CML, adherence to treatment correlates with the probability of achieving an improvement in long-term clinical outcomes, including major molecular response and improved event-free survival [ 37- 39].
Its genetic improvement is essential to provide protection against major diseases and improve chocolate quality.
Mr Prabhu promised to make India's railways safer, build more lines, increase the speed of journeys on nine major routes, and improve the experience of travelling with wi-fi in stations.
It will award $9 million to five cities that come up with bold ideas for solving major problems and improving city life.
The Bloomberg Philanthropies Mayors Challengee is a competition designed to inspire America's mayors to generate innovative ideas that solve major challenges and improve city life.
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In patients with acute coronary syndromes, fondaparinux is similar to enoxaparin in reducing the risk of ischemic events, but it also substantially reduces major bleeding and improves long term mortality and morbidity.
"We believe in the power of innovation to tackle major challenges and improve millions of children's lives in Viet Nam," says UNICEF Viet Nam, 2 November 2013 – UNICEF today concludes the UNICEF Mobile Hackathon 2013 with the Final Demo Day spotlighting the final event winners OCEAN 4 and Ga Trong, rewarded for their innovative mobile applications designed to tackle children's issues in Viet Nam.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com