Sentence examples for major and direct from inspiring English sources

It's clear that this White House saw an opportunity to drive a major — and direct — contrast between President Obama and his potential Republican rivals and took it.

While latent infection of KSHV plays a major and direct role in tumorigenesis, viral lytic replication also makes significant contributions to this process.

Any disruption to trade in coffee would have major and direct negative implications for the livelihoods of rural populations in many developing countries.

In another more recent report, Drosophila dCREB-A as well as mammalian CREB3L1 and CREB3L2 were found to be major and direct regulators of secretory capacity [ 23].

In this study, we provide multiple lines of evidence that the PP4 complex, with Pph3 as the catalytic subunit, is the major and direct phosphatase of Maf1.

This rapid, selective, and massive accumulation in mitochondria provides strong evidence that these organelles are a major and direct target of the biological effects of this small molecule.

The Cruz Reader and Cruz StoryPad will be available from most major retailers and direct from Velocity Micro in August with the Cruz Tablet following on September 1st.

Another 17% were sold at major chains, and direct mail/catalogs accounted for 6%.

Meet with representatives of each major department and direct your sales pitch to explain how your software can benefit their organization as a whole.

Together, these results indicate that extracellularity has a major, and likely direct, impact on mammalian protein evolution.

Majors plan and direct day-to-day military operations for Army battalions, the units primarily responsible for waging the counterinsurgencies in Iraq and Afghanistan.