Sentence examples for major analytical challenge from inspiring English sources

The extremely short half-life of PDGF in plasma (2 minutes) is a major analytical challenge.

Under such circumstances, the issue of distinguishing truly functional variants from background neutral variations is a major analytical challenge to this approach.

The efficiency of protein separations presents a major analytical challenge.

The structural elucidation of the metabolites of interest remains a major analytical challenge in the metabolomics workflow.

However, differentiation of d/ l-peptide epimers by MS represents a major analytical challenge because the peptide epimers share identical masses and primary structures.

The confident identification of these metabolites on a high-throughput scale, however, remains a major analytical challenge because of their chemical and structural diversity.

In particular, the major experimental and analytical challenges encountered (and inferred to result from so-called "nanonugget" formation) are described.

The problem is a complex one of scheduling and placement, and its optimization presents major theoretical and analytical challenges.

We describe the setting, design and analytical framework of the Harvard Forest Hemlock Removal Experiment (HF-HeRE), a multi-hectare, long-term experiment that overcomes many of the major logistical and analytical challenges of studying system-wide consequences of foundation species loss.

However, these estimates are subject to major methodological and analytical challenges.

Despite gene duplication representing an analytical challenge for GBS, it is also a major source of evolutionary novelty (Ohno 1970; Lewis 1951).