We also repeated our major analyses with the inclusion criteria used in a recent article addressing the same issue (14): age 30 60 years, arterial blood pressure <140/90 mmHg, total serum cholesterol <7.8 mmol/l, and serum triglycerides <4.6 mmol/l.
32 All the relevant variables included in the major analyses were used in the multiple imputation models, as was the outcome (age at death).
The major analyses were based on the information derived from the abstract evaluation and the data base searches.
Since oral-pharyngeal and oesophageal cancers are more frequent in men, and to avoid heterogeneity between sexes of the covariates included in the model, the major analyses were restricted to men and the results on female subjects were given in the text only.
AT conceived of the study, performed major analyses, and drafted the manuscript.
Spatial network analysis, visual analysis and descriptive statistics methods were the major analyses used to produce the outputs: maps, tables, and graphs.
Thence the data were exported to AM software for the major analyses, which made use of the weights and replicate weights and took into account the multistage sampling.
The major analyses lagged by 2 years and the sensitivity analysis lagged by 5 years, both strengthened our confidence in the validity of the study findings.
For the major analyses, hierarchical logistic regressions were used for the outcome variables of professional contact and non-professional contact, each coded as no contact (0) versus any contact (1).
This second finding, summarized in Table 8, indicates little or no need for adjustment for confounding from current smoking in the major analyses involving all cases and controls because the second criterion for being a confounder is not met.
