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Major amputation: amputation through or above the ankle joint.
32 subjects with diabetic foot in the structured health care group underwent major amputation (amputation above the ankle) during hospital treatment (major amputation rate 4.7%).
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The type of procedure performed was noted and divided into four categories: minor amputation (amputation below the ankle joint or necrosectomy), major amputation (lower and upper leg amputation), bypass surgery (femoropopliteal, femorocrural, iliofemoral, and aortofemoral bypass), and femoral endarterectomy.
The objective of this study was to assess the prognostic value of a high or immeasurable ankle-brachial index (ABI) at baseline for major amputation and amputation-free survival (AFS) in patients with critical limb ischemia (CLI).
Factors that increase risk for a major amputation include race, skin ulcers, gangrene, and prior amputation.
To evaluate the influence of secondary infection on major amputation in chronic critical leg ischemia (CLI).
In follow-up, 1 patient with a prior history of septic diabetic foot required major amputation.
Major amputation was required in two of three patients following early graft failure.
Significantly more diabetics underwent major amputation (p < 0.02) than non diabetics.
During the two year follow-up 22 subjects underwent major amputation (major amputation rate during follow-up 3.2%).
In case of the outcome first major amputation, death without major amputation was also counted as a censoring event.
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