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1, 2 Angiotensin-II (A-II), the major active peptide, activates A-II type 1 receptor (AT1R) to provide vasoconstriction and hypertension.
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Angiotensin II (Ang II), the major biologically active peptide of the renin-angiotensin system, mediates its effect through the AT1R and the angiotensin receptor type 2 (AT2R).
Another group of minor active peptides are the virotoxins, which consist of six similar monocyclic heptapeptides.
LF-6 is a modified antibacterial peptide derived from LFP-20, a major active ingredient of porcine lactoferrin, whose antibacterial activity is 200 times higher than its native protein counterpart.
OGF is a constitutively active peptide that has a receptor-mediated action in the negative regulation of neointimal growth, a major cause of restenosis.
Triangles denote major active volcanoes.
Oppositely, Tanimoto coefficient between an active peptide and a non-active peptide is smaller because these two features are different to each other.
Active peptides were selected by the design parameter 'V' or 'Pr', which reflects the probability of active peptide conformations for constrained and unconstrained peptides, respectively.
Purple broken lines are major active faults (HERP 2017).
Major active faults are drawn as red lines.
Prenylflavonoids are major active components of Epimedii wushanensis herba (EWH).
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