Sentence examples for major active form from inspiring English sources

Yet, there is considerable evidence that the high-molecular weight (HMW) complex of adiponectin is the major active form of this adipokine.

This study was designed to examine the dysregulation of E23K on insulin sensitivity in the presence of long-chain fatty acyl CoA (LC-CoA), a major active form of free fatty acids.

One product, 3,5,3'-triiodothyronine (T3), is the major active form of the thyroid hormone, and about 80% of the T3 produced in the body is derived extrathyroidally.

During early embryonic development, the major active form of retinoids, all -trans retinoic acid (atRA), regulates germ layer formation, body axis formation, neurogenesis, cardiogenesis, and the development of pancreas, lung, and eye.

1 The major active form of GLP-1 is a GLP-1(7–36) amide 2 and, following its release into the circulation, GLP-1(7–36) amide undergoes rapid enzymatic degradation by dipeptidyl peptidase-4 (DPP-4) 3 into GLP-1(9–36) amide by the removal of an N-terminal dipeptide, which is an inactive form.

On the other hand, the HMW multimers appear the major active forms in mediating the metabolic effects of adiponectin even in young children [9], [10], [11].

The major active forms have 13 to 36 residues, such as apelin-13.

Hydroxyl radical is a major active oxygen species formed in the biological system with capability to conjugate with nucleotides in the DNA resulting in strand breakage which could lead to various diseases.

It has been recently suggested that the HMW adiponectin complex is the major source of the active form of this protein (Pajvani et al, 2004).

Finally, we did not analyze concentrations of high-molecular-weight (HMW) adiponectin, which is the major source of the active form of this protein [ 35].

The αGC residues Glu526 and Cys595 are located in interfacial regions that would undergo major conformational changes in the active form.