Sentence examples for major activators of from inspiring English sources

Dendritic cells (DCs) are major activators of T cells, providing signals that drive their expansion and differentiation.

We identify buttonhead and empty spiracles as the major activators of cdc25 string) expression in mitotic domain 2. The effect of these activators is balanced through repression by hairy, sloppy paired 1, and huckebein.

Since TACE is one of the major activators of TNF-α, TACE-inhibition has been implicated as a promising anti-inflammatory approach [17], [24].

These cytokines are major activators of SOCS/CIS signalling, particularly SOCS1 and 3 in granulocytes and lymphocytes [ 18, 45].

Proteases of the coagulation system are the major activators of PARs, suggesting that PARs have evolved to regulate cellular functions associated with the response to vascular injury.

These cytokines are major activators of SOCS/CIS signalling, particularly SOCS-1 and -3 in granulocytes and lymphocytes (Hilton, 1999; Dogusan et al, 2000).

TNF exhibits potent antitumoral activity, but also represents a major activator of innate immune responses with strong pro-inflammatory and pathophysiological activities [ 11].

Platelet-activating factor is a major activator of neutrophils, which have been demonstrated to play an important role in the pathogenesis of sepsis.

nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) was the major activator of C7ORF41 that in turn repressed NF-κB activity by inhibiting its phosphorylation at serine 536, while MAPK/ERK was the potent repressor of C7ORF41.

In synovium, IL-1β is a major activator of SFs by promoting the activation of NF-κB and MAP kinases [ 1].

Myc/Max dimers mainly activate gene expression, and are a major activator of cell proliferation of growth.