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The phrase 'major act' is perfectly correct and usable in written English.
You can use it to refer to an action or event of particular importance or significance, e.g. "The passing of this new bill is a major act for the environment".
Exact(59)
Any major act can achieve that.
Bremer's first major act was not auspicious.
His first major act as Shatner was his most inspired.
The NDEA stands as a major act of reform.
Dido is the second major act to be sued this year by an album cover-star.
Almost every other major act across all the stages on each night will be male.
The Young Vic's current season of early Brecht plays is a major act of reclamation.
He dissolved the cabinet without explanation in his first major act since assuming executive powers.
It doesn't seem a likely spot for a major act of innovation.
Open dissent in Cuba is a major act, and he hasn't done that.
The son's first major act was to push through the biggest tax cuts in US history.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com