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Nuclear DNA mutations can account for combined respiratory chain deficiency by negatively affecting mitochondrial maintenance, translation and/or transport.
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Its presence in the wobble position probably allows better binding of the tRNA to the cognate codon, possibly helps the tRNA to discriminate against codons ending with A [ 78] and to aid in phase maintenance during translation; iii) the rare isoleucine AUA codon is translated by a minor tRNA-Ile, like in all bacteria.
Mutations affecting mitochondrial genome maintenance and translation were highly represented in sensitive mutants in either growth phase.
Method maintenance, robustness and translation to regulatory requirements have been important barriers to implement the method.
Successful application of SCT constructs for RT maintenance may support translation of our RT program for diabetes prevention into community settings.
Many of the interacting proteins occupy essential hub positions in cellular protein networks, with key roles in chromatin organization, transcription, translation, maintenance of cell architecture and protein quality control.
Type I circuits, in which the miRNA and its target are regulated together would allow for modulation of protein translation, maintenance of cellular homeostasis, or modulation of changes in local protein concentrations.
Numerous genes related to DNA maintenance and replication, translation, ribosomal biosynthesis and RNA processing as well as biosynthesis of the cell envelope and flagellum and several components of the chemotaxis signal transduction complex were up-regulated only in young cells.
In addition to inhibition of autophagy by binding to Beclin 1, ICP34.5 can also regulate autophagy through regulation of eIF2 α. eIF2 α plays a central role in the maintenance of mRNA translation.
The mitochondrial proteome consists of ~1300 proteins, therefore the remaining 99% of mitochondrial proteins are nuclear encoded, including all of the protein machinery required for mtDNA replication, maintenance, transcription and translation (Calvo and Mootha, 2010).
Thus, we suggest that while auxin changes are probably mainly related to cell wall in sensitive fruit, cytoplasmic auxin in tolerant fruit may be related to the maintenance of the translation machinery and the control of ROS.
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