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Maintenance therapy reduces -but does not normalize- Th17 expansion.
It is estimated that, in patients with schizophrenia, maintenance therapy reduces the risk of relapse by about two-thirds [ 24, 25].
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Research also suggests that intermittent fasting can decrease inflammation, reduce fat tissue, and help weight maintenance.
In addition, one study has shown that beclometasone/formoterol maintenance and reliever therapy reduces exacerbations more effectively than beclometasone/formoterol plus as-needed SABA.
During long-term continuous therapy or with repeated treatments, dose adjustment by concurrent measurements of drug concentration or clinical therapeutic targets (e.g. degree of myelosuppression during ALL maintenance therapy) may reduce the need for outcome prediction prior to treatment.
Collaborative care trials have proven their efficacy on sustained recovery of depressive disorder and continuation and maintenance therapies can reduce recurrence [ 58, 59].
Those undergoing relaxation therapy reduced awake time by only 16percentt.
Similarly, budesonide/formoterol maintenance therapy improved asthma control and reduced future risk compared with budesonide alone in the Formoterol and Corticosteroids Establishing Therapy (FACET) study.
Another study of 511 patients with longstanding, refractory RA found that long-term maintenance therapy with infliximab continues to reduce disease activity [ 62].
It may be the case that patients are unaware of the relapsing remitting nature of the disease [ 10], and the importance of maintenance therapy during quiescent periods to reduce the probability of a disease flare [ 11- 13].
Although the AUA acknowledges that maintenance therapy is more effective in reducing recurrences than induction therapy alone, routine maintenance is considered optional in patients with intermediate-risk disease given that the side-effects and costs associated with treatment may outweigh the benefits in these patients.
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