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From this, we conclude that RA signaling is not required to define the position of the future liver but rather interferes with liver maintenance or differentiation program.
New factors are constantly connected to stem cells regulating their maintenance or differentiation, e.g. growth factors, epigenetic modifiers, neurotransmitters, and extracellular matrix proteins.
Our data suggest that IL-23 is required for the optimal production of IL-22 from splenocytes, but not for the maintenance or differentiation of these cells.
Whether Wnt signaling regulates stem cell maintenance or differentiation has been extensively debated, and some genes have both inhibitory and activating abilities dependent on the state of Wnt signals [16].
These observations imply that Tai participates in niche formation and/or GSC maintenance or differentiation.
List of Tested Compounds, Related to Figure 1 List of all the compounds tested for their capacity to enhance human liver culture proliferation, long-term maintenance, or differentiation.
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Subsequently, these cells/hydrogels systems were cultured in maintenance medium or differentiation medium.
Maintenance medium or differentiation medium was changed twice a week without damaging the gels.
The studies discussed previously suggest that microenviromental changes (i.e., niche deterioration) are critical for loss of stem cell maintenance or to drive differentiation over self-renewal and vice versa.
Moreover, galectin-9-deficient mice demonstrate significantly decreased Tregs, indicating that Galectin-9, in part, regulates differentiation, maintenance or expansion of Tregs expressing Foxp3 [8].
Meanwhile, the excluded iPS cell lines (ones that showed spontaneous differentiation during maintenance, or had a high copy number of transgenes), demonstrated a significant diversity of differentiation (Fig. S7).
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conservation or differentiation
maintenance or division
maintenance or user
maintenance or something
maintenance or path-building
maintenance or error
maintenance or reduction
maintenance or reestablishment
maintenance or reliability
maintenance or rebel
maintenance or upgrade
maintenance or outage
maintenance or decline
maintenance or enhancement
maintenance or equilibrium
maintenance or decline…
maintenance or disaster
maintenance or repair
maintenance or hassle
maintenance or system
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