Sentence examples for maintenance of tumor from inspiring English sources

For example, ROS are involved in cell proliferation, cell cycle progression, cell survival, energy metabolism, cell motility, angiogenesis, and maintenance of tumor stemness37.

The key players involved in the development and maintenance of tumor neovasculature are vascular endothelial growth factor (VEGF) and its receptors (VEGFRs), and therefore VEGF/VEGFR signaling pathways have been a focus of anticancer therapies for several decades.

On the other hand antioxidants can promote the survival of detached cells from extra cellular medium playing dual activities with respect to tumorigenesis through inhibition of tumorigenesis by preventing oxidative injuries to DNA and otherwise maintenance of tumor by promoting cell survival via metabolic rescue.

To prove the special role of CD44+ cells in initiation and maintenance of tumor when administered EC even in minimal doses, it was of interest to comparatively assess the tumorigenic capacity of isolated CD44+ and CD44– fractions when administered at various concentrations.

Their continued expression is essential for the malignant transformation and maintenance of tumor cells [5], [6], [7], [8], [9].

In summary, we observed increased vascular leakage and altered vessel structure in tumors from Cd34−/− mice, suggesting a role for CD34 in the maintenance of tumor vessel integrity, a limiting factor in tumor growth.

Furthermore, we demonstrate that the MYC-driven epigenetic reprogramming favors the formation and maintenance of tumor-initiating cells endowed with metastatic capacity.

Dendritic cells (DCs) are crucial for the induction and maintenance of tumor-specific immune responses.

One of these regions, termed transfer DNA, induces tumor formation and is found in all established plant tumor lines; the other, termed the virulence region, is essential for the formation but not the maintenance of tumors.

Although latency drives immortalization of infected cells, the lytic cycle is vital for the maintenance of tumors in vivo, likely due to the induction of paracrine factors that function in immune evasion, proliferation and angiogenesis [2].

Telomerase, a ribonucleoprotein critical in permitting limitless replication, has been found to be critically important for the maintenance of tumor-initiating cells (TICs).