Sentence examples for maintenance of repressed from inspiring English sources

First, Chp1 contributes to de novo assembly at all sites of heterochromatin, yet contributes to the maintenance of repressed chromatin exclusively at centromeres (Sadaie et al, 2004).

A function of HDACs in silencing of PcG target genes has also been established (Schuettengruber et al. 2007), suggesting that multiple interactions between chromatin-modifying activities could provide stability and contribute to the maintenance of repressed chromatin.

These findings are of significant worth, as they point out the importance of the role of histone deacetylases in maintenance of repressed chromatin architecture at PML RAR α binding sites.

Compelling evidence indicates that DNMT1 plays an essential role in the maintenance of transcriptionally repressed chromatin.

Although MBD3 does not itself bind directly to methylated DNA, several lines of evidence suggest that MBD3 does play a role as part of the NuRD complex in the maintenance of transcriptionally repressed chromatin.

Thus, we propose that a HAND1-associated differentiation program acts to limit cancer development and thus by extension, provides a functional link between gene silencing, maintenance of proliferation, repressed differentiation by PRC2, in the context of tumorigenesis.

Wegner calls this "the ironic return of repressed thoughts".

What are memories if not forms of repressed knowledge?

In Arabidopsis, FLC is repressed by vernalization in two phases, first by a repression of expression by cold and secondly by a stable maintenance of repression that persists after the plant returns to warm temperatures [5], [114].

The maintenance of open and repressed chromatin states is crucial for the regulation of gene expression.

This makes sense because, as well as the role played by miRNAs in the regulation of the switch between latency and lytic replication, LANA is known to function in the maintenance of latency by repressing the promoter of RTA, and by binding directly to the RTA protein to prevent its self-reactivation [21].