Arl13b is capable of self-associating via N domain, and overexpression of N domain inhibits not only cilia formation but also the maintenance of pre-generated cilia.
Functional outcomes in patients treated with PCCP, as evaluated by the improved mHHS, return to pre-fracture mobility, and maintenance of pre-surgery domicile status at the 1-year follow-up period should be considered excellent when compared to other studies and considering the status of our patients.
One could make the case that true risk reduction is in restoring NGR rather than in maintenance of pre-diabetes.
Furthermore, several genome variants can be delivered simultaneously to individual cells, thus favoring the maintenance of pre-existing sequence polymorphisms even under extreme bottlenecks.
The likely reality is that peripheral antigens are critical for both the generation of new Treg cells and the maintenance of pre-existing Treg cells.
The latter is relevant as epidemiological studies have shown an association between maintenance of pre-pregnancy level of physical activity during pregnancy and reduced risk of gestational diabetes and pre-eclampsia [ 13, 14].
While residual PRC1 binding or epigenetic maintenance of pre-existing PRC2 could be responsible for this, previously reported PRC1-independent targeting mechanisms could also play a central role in remaining PRC2 occupancy (Simon and Kingston, 2013).
To study the molecular mechanisms that regulate the maintenance of pre-GEPCOT qNSCs and GEPCOT NICs in vivo we generated a floxed allele of Bmi-1 and conditionally deleted Bmi-1 using Nestin-Cre (Tronche et al., 1999).
Although male development and maintenance of pre-copulatory male sexually selected traits other than body size or mass are costly (i.e. [ 21]), and can potentially covary with the expression of ejaculate characteristics (i.e. [ 22]), inter-specific studies involving male armaments or ornamental traits remain scarce.
Post-synaptic myonuclei are specialized for the expression of synapse-enriched genes required for the development, differentiation, consolidation and maintenance of both pre- and post-synaptic components (Schaeffer et al., 2001; Hippenmeyer et al., 2007).
Maintenance of a pre-ictal AAI value ≧ 26 was associated with an increased incidence of successful seizure activities and a longer seizure duration.
