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However, these treatments were apparently performed at a stage following the initial polarization, meaning that microtubules may be dispensable for the local steady-state maintenance of polarized distribution but not for the initial polarization.
Based on comparative biology studies between S. cerevisiae and Ashbya, it was found that multiple Rho-protein modules are involved in processes of cell polarity establishment, cell wall integrity and maintenance of polarized hyphal growth (Wendland and Philippsen, 2001).
CASK is a scaffolding protein that participates in maintenance of polarized epithelial cell architecture by linking membrane proteins and signaling molecules to the actin cytoskeleton.
These results provide a link between the transcriptional regulation of hyphal extension presented here (Fig. 9) and the known cellular requirements for maintenance of polarized growth and associated structures such as the spitzenkörper.
We first addressed the role of actin cables in the establishment and the maintenance of polarized growth upon exit from quiescence using a thermo-sensitive (ts) mutant strain conditional for formin function: bni1-FH2#1 bnr1Δ.
A cyclical regulatory network contributes to the establishment and maintenance of polarized cell growth [ 137].
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It differs from the most common view of polarity, in which the role of the cytoskeleton is restricted either to the maintenance of the polarized state [14], [17] or to the motility subsequent to gradient sensing [41].
Several questions remain concerning the formation and maintenance of a polarized distribution of chemoreceptors: by which mechanisms do receptors become asymmetrically localized?
In our model, the formation and maintenance of a polarized distribution of receptors results from an interplay between MT-induced trandport andiffusionon.
We are interested in the processes that establish polarity in tip-growing cells and this study focuses on formation and maintenance of a polarized endomembrane array in Silvetia zygotes.
Whether TRPM7 is also involved in the maintenance of myosin IIA polarized distribution and activity in migrating DCs is an opened question.
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