Takase, O. et al. The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells.
Since pluripotent colony morphology correlates closely with the maintenance of pluripotency, the mechanisms by which these colonies form and organize may be important for controlling somatic cell reprogramming.
Geometric factors including the size, shape, density, and spacing of pluripotent stem cell colonies play a significant role in the maintenance of pluripotency and in cell fate determination.
Lavagnolli, T. et al. Initiation and maintenance of pluripotency gene expression in the absence of cohesin.
Sox2 is a transcription factor required for the maintenance of pluripotency.
The second, typified by the human, monkey, and pig, is often named epiblast-type and requires FGF2 for self-renewal and maintenance of pluripotency.
James D, Levine AJ, Besser D, Hemmati-Brivanlou A. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells.
The maintenance of pluripotency of CSCs under various pathophysiological conditions requires a complex interaction between various cellular pathways including those involved in homeostasis and energy metabolism.
The origins of the observed heterogeneity and its roles in the maintenance of pluripotency and the lineage specification of stem cells remain unclear.
This review examines the role of hypoxia in regulating stem cell biology, specifically focusing on growth, maintenance of pluripotency, differentiation, and production of growth factors.
The phosphatidylinositol-3-kinase (PI3K /Akt pathway is important for the maintenance of pluripotency in stem cells.
