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Aberrations in alternative splicing were found as a cause or a contributing factor to the development, progression, or maintenance of numerous diseases.
The city is responsible for the maintenance of numerous sports and recreation fields, including 40 grass/sand/soil sports fields, five FieldTurf fields, 35 ball diamonds, several all-weather surfaces, a bowling green, a croquet/bocce court, and a cricket pitch.
The IL-21 cytokine has been implicated in the development and maintenance of numerous autoimmune and inflammatory diseases in both animal and human models [1].
IL-21 has been associated with the development and maintenance of numerous autoimmune and inflammatory diseases in both animal and human models.
Finally, several modes of natural selection could operate over regulatory regions that would result in a rapid turnover of functional binding sites and maintenance of numerous cryptic signals, such as compensatory selection, stabilizing selection or selection for robustness to mutation.
Therefore, the establishment and maintenance of numerous genetic registries over recent decades has had an important role in the conservation of medical genetic data.
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Cell migration is a central, highly integrated multistep process required for maintenance and development of numerous physiological processes.
CD4+CD25+FOXP3+ regulatory T cells (Treg) are of critical importance for the maintenance of immune homeostasis, as numerous experimental mouse models for autoimmune diseases correlate the presence of functional Tregs with amelioration of disease severity [1], [2].
After duplication, the probability of fixation and maintenance of duplicates depends on numerous variables, and a combination of stochastic but also adaptive mechanisms take place.
Epithelial cell polarity is crucial for development and maintenance of tissue integrity in numerous developmental processes, such as neurulation or organogenesis, but also in homeostatic processes in differentiated adult tissues.
It is much more difficult to understand why, in the case of the Irx genes, there would have been systematic events leading to cluster maintenance after numerous instances of gene duplications, unless postulating some particular properties of the Irx genomic region that would, by itself, favor the conservation of the physical link between the duplicated genes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com