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All three cooling methods have already been used in awake subjects for induction and maintenance of mild hypothermia.
However, rewarming was reported by Kliegel and colleagues [ 21], who proposed maintenance of mild hypothermia by repeated cold infusions.
However, we cannot exclude the possibility that maintenance of mild diabetic neuropathy may also have prevented progression of diabetic retinopathy/nephropathy.
Combining external warming to prevent vasoconstriction with meperidine administration might therefore prove effective for the induction and maintenance of mild therapeutic hypothermia.
The aim of this study was to investigate the feasibility and safety of non-invasive surface cooling for induction and maintenance of mild hypothermia (32 to 34°C) in healthy, conscious volunteers.
So far, the majority of therapeutic hypothermia research has involved cardiac arrest patients, in whom the induction and maintenance of mild hypothermia is facilitated by post-anoxic coma, anesthesia and paralysis to avoid shivering.
Similar(54)
It is unclear if the prevention of progression of diabetic retinopathy/nephropathy is results from inhibition of aldose reductase by epalrestat or a secondary effect because of maintenance of milder diabetic neuropathy, or a combination of both.
This combination can therefore be considered a recommendable and feasible regimen for induction and maintenance of therapeutic mild hypothermia.
The aim of the present study was to investigate the feasibility and safety of a temperature care bundle, started in the out-of-hospital setting, combining surface, intravenous and endovascular cooling for induction and maintenance of prereperfusion mild hypothermia in awake patients with STE-ACS.
These findings offer evidence that ligand-activated progesterone receptor mechanisms contribute to the maintenance of lordosis behavior in the presence of mild stress.
In conclusion, available data do not support the use of pediatric regimens in adult LCH, indicating that the concept of mild induction followed by maintenance therapy probably cannot be translated to adults.
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