Sentence examples for maintenance of malignant from inspiring English sources

As a potential role in intercellular adhesiveness and maintenance of malignant tissue architecture, the results indicate that miR-888 is a repressor of the AJ pathway in MCF-7 cells and that up-regulation of miR-888 contributes to aggressiveness in MCF-7 SP cells.

We will discuss the role of apoptosis and its deregulation during the induction, progression and maintenance of malignant disease.

Regarding the former, it has also been demonstrated that H3K18 hypoacetylation is linked to the maintenance of malignant phenotypes and poor prognosis in cancer.

Thus, continued inactivation of the tumour suppressor was required for the maintenance of malignant tumour growth in orthotopic MiaPaCa-2 tumours.

In our opinion, the detection of HPV-53 in metastatic cells far from primary tumor would support the role of this virus in the maintenance of malignant status.

One possible explanation for this may be oncogene addiction where cancer cells are dependent upon or 'addicted' to one or several genes for maintenance of malignant phenotype and cell survival.

The expression of some TAAs is irrelevant for the maintenance of the malignant phenotype, with unstable expression in the malignant cells (e.g., MUC16).

We face the exciting prospect that every genetic lesion involved with the generation and maintenance of the malignant phenotype will soon be defined in all malignancies including breast cancer.

During latent infection, EBV continuously expresses a number of viral genes which are essential for cell transformation and maintenance of the malignant phenotype of EBV-related tumors.

In recent years, research on treatment strategies has proposed several options, including the role of HPV E5, E6, and E7 oncogenes, which are retained and overexpressed in most of the cervical cancers and whose respective oncoproteins are critical to the induction and maintenance of the malignant phenotype.

Similar to normal stem cells, CSC self-renewal is required for long-term maintenance of the malignant clone.