Sentence examples for maintenance of intercellular from inspiring English sources

These studies showed that loss of E-cadherin-mediated adhesion enabled acquisition of an invasive phenotype, suggesting that maintenance of intercellular adhesion and tissue organization plays a crucial part in suppressing the incipient stages of squamous cell cancer progression.

It seems likely that tightly controlled physiological levels of Src signals in AJs are critical for the assembly and maintenance of intercellular adhesion, while dysregulation results in abnormalities of cell junction formation and migratory behaviour that might lead to significant pathology.

VE-Cadherin (VECad) is essential for the maintenance of intercellular contacts.

E-cadherin (E-cad), one of the key cadherins, plays a major role in the establishment and maintenance of intercellular adhesion, cell polarity and tissue architecture (Takeichi, 1991).

E-cadherin is one of the key cadherins and plays major roles in the establishment and maintenance of intercellular adhesion, cell polarity and tissue architecture [ 3].

The epithelial function requires the maintenance of intercellular junctions (zona occludentes) and the organisation of cellular polarity (brush border and lateral intercellular spaces).

Catna1 (catenin alfa 1; cadherin-associated protein; Ctnna1) is an intracellular protein that associates with cadherins and cytoskeleton and is required for the formation and maintenance of functional intercellular adhesion complex [34].

Several transmembrane proteins are involved in the establishment and maintenance of the intercellular adhesion.

Genetic ablation of Dsc1 and Dsg3 results in epidermal blistering in transgenic mice, illustrating the importance of these molecules for the maintenance of normal intercellular adhesion (Koch et al, 1997; Chidgey et al, 2001).

Src activation is a master event in the preservation of normal cell homeostasis, and it regulates cytoskeleton organization, maintenance of normal intercellular contacts, and cell adhesion, motility, proliferation and survival.

To our knowledge, this study is the first to demonstrate that PCDH1, which has been identified as an airway hyperreactivity-susceptibility gene, has an important role in the formation and maintenance of the intercellular junctions that comprise the airway epithelial barrier.