Sentence examples for maintenance of glomerular from inspiring English sources

CD80 (B7-1) can be expressed on injured podocytes, and administration of abatacept (modified CTLA4-Ig based on a natural ligand to CD80) has been associated with sustained normalization of urinary protein excretion and maintenance of glomerular filtration rate in experimental and clinical settings.

Given the roles of EHD proteins in regulating endocytic recycling, it is likely that loss of EHD3 and EHD4 causes aberrant trafficking of key receptors such as VEGFR2, that are critical for maintenance of glomerular endothelial cell function and endothelial-cell dependent inter-cellular signaling critical for glomerular health.

These findings suggested that β-catenin is a critical regulator of the maintenance of glomerular filtration barrier and its function.

D2-40 (playslanin) plays a crucial role in preventing cellular adhesion and is strongly involved in the maintenance of glomerular permeability [ 22].

Proliferation and apoptosis of mesangial cells (MC) are important mechanisms during nephrogenesis, for the maintenance of glomerular homeostasis as well as in renal disease and glomerular regeneration.

A number of angiogenic growth factors are involved in the development of the kidney and in the maintenance of glomerular structures and the glomerular filtration barrier function in adults.

These findings indicate that deposition of amyloid in the glomerular tuft significantly reduces glomerular filtration rate, impairs maintenance of the glomerular filtration barrier and leads to subsequent protein loss, which may enhance progression of renal fibrosis.

The development and maintenance of normal glomerular structure and function requires successful signaling and coordination between all glomerular cells, as shown by the critical requirement for vascular endothelial growth factor-A (VEGFA) production by podocytes for normal endothelial and mesangial cell development and function [3], [4].

Podocytes are highly specialized epithelial cells with complex actin cytoskeletal architecture crucial for maintenance of the glomerular filtration barrier.

The structural and functional integrity of the podocyte is essential for the maintenance of the glomerular filtration barrier and components of the actin cytoskeleton have been shown to be crucial for podocyte function and response to stress and injury.

These results suggest that the MCs also adapt to the pregnancy, thereby contributing to the maintenance of the glomerular surface area even in the presence of high levels of Ang II.