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Selective coefficients for the maintenance of genes for regulation and for rRNA genes may be reduced in an intracellular environment, resulting in the loss of these genes.
Their diversification is characterised by (i) ancestral gene duplications preceding species separation followed by maintenance of genes, (ii) ancestral duplications followed by gene loss in some of the species, and (iii) recent duplications after divergence of species.
Within this multigenic family, maintenance of genes during the successive genome duplications is in good agreement with expected behavior of genes subject to dosage constraints (highly expressed genes are preferentially retained as duplicates[ 9]).
Rather, this protein transits between the nuclear interior and NPCs, suggesting that Nup2p-dependent recruitment and/or maintenance of genes at the periphery does not dictate stable NPC association.
To gain insight into the evolutionary maintenance of genes with different levels of methylation, we first investigated whether genes belonging to distinct CpG O/ E classes showed differences in their conservation of CpG O/ E status over evolutionary time.
Under this model, natural selection would not only affect and maintain the amount of genetic diversity in a given locus but also its relative position in the genome, favoring the maintenance of genes that could be contribute to adaptations under strong positive selection in areas with higher relative rates of recombination, such as the subtelomeric regions.
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These results demonstrate the role of Dicer-associated RNA binding proteins in maintenance of gene silencing fidelity.
The epigenetic contribution to the regulation and maintenance of gene expression patterns by histone modifications is well established in eukaryotes.
A key issue in the long-term survival of this metapopulation is the maintenance of gene flow (by preserving the connectivity of the habitat network).
The complex control and maintenance of gene expression and modulation are regulated by a multitude of molecular and cellular mechanisms that layer on top of the genetic code.
In the case of the flowering time regulator FLC, chromatin compactness and histone modifications are controlled by environmental cues and ensure faithful maintenance of gene repression after vernalization.
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