Suggestions(5)
Exact(7)
Evidence is in favour of the view that both formation and maintenance of gap junctions is critically dependent on the presence of correct mechanical stabilization [36].
Collectively, we demonstrated that the absence of ST2-mediated signalling pathway in non-hematopoietic cells protects mice against DSS-mediated colitis with maintenance of gap junctions.
The cells were morphologically normal, as assessed by light and electron microscopy, with maintenance of gap junctions between cells and limited vacuolation.
Interestingly, Stat3 inhibition in two NSCLC lines which exhibit extensive junctional communication (QU-DB, SK-LuCi6) abolished GJIC, indicating that Stat3 does in fact play a positive role in the maintenance of gap junction function.
On the contrary, Stat3 inhibition in lines displaying extensive GJIC (QU-DB, SK-LuCi6) suppressed junctional permeability, indicating that Stat3 activity is actually required for the maintenance of gap junction function in these lung cancer lines.
We then examined the possibility that Stat3 might play a positive role in the maintenance of gap junctional permeability, by assessing the effect of Stat3 inhibition upon GJIC levels in QU-DB cells which have low Src activity and extensive GJIC.
Similar(53)
We suggest that maintenance of tree fall gaps as a heterogeneous habitat and dead wood resource is crucial for promoting species richness.
Thinking in terms of the maintenance gap, then, takes all important factors into consideration when it comes to maintenance and aging, so that all questions can be grouped in two overarching questions.
Intercellular communication in the eye lens relies on an extensive network of gap junctions essential for the maintenance of lens transparency.
Based on our identification of functional gap junctions in CSCs and the efficacy of gap junction inhibitors on attenuating CSC maintenance, we wanted to determine which connexins were responsible for these effects.
The possible mechanisms supporting its use include: anti-inflammatory action, oxytocin antagonism (producing relaxation of smooth muscle), maintenance of cervical integrity, and reduced gap-junction formation [ 109].
More suggestions(15)
maintenance of plant
maintenance of user
maintenance of normothermia
maintenance of objectivity
maintenance of board
maintenance of pluripotency
maintenance of equipment
maintenance of hERG
maintenance of population
maintenance of temperature
maintenance of railway
maintenance of biodiversity
maintenance of coup
maintenance of stability
maintenance of membrane
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com