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Consequently, maintenance of endogenous H2S production might attenuate sepsis-induced metabolic alterations; due to its effects on glucose utilization, its protective effect on mitochondrial function [18], and the potential of limiting the development of liver steatosis [1].
Here we took a systematic approach to identify small molecules that support self-renewal of naive human ESCs based on maintenance of endogenous OCT4 distal enhancer activity, a molecular signature of ground state pluripotency.
The JMD binding to p120-catenin has been already implicated in the stable maintenance of endogenous cadherins [ 13, 92].
Furthermore, the maintenance of an r2-specific migration pattern is correlated with the maintenance of endogenous Hoxa2 expression.
BMI1 participates in the maintenance of endogenous stem cells, partly by repressing genes involved in cell death and senescence [ 34].
NQO1 is a homodimericflavoprotein and many functions have been proposed, such as xenobiotic detoxification, superoxide scavenging, modulation of p53, maintenance of endogenous antioxidants, and proteasomal degradation [ 6].
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Germ cell infections by exogenous retro-viruses occurred millions of years ago and led to the stable maintenance of human endogenous retroviruses (HERVs) into the human genome.
In summary, CR-SPRC displayed a better cardioprotective effect than SPRC, which is consistent with a prolonged maintenance of the endogenous H2S concentration.
Both phase II trials using the two different anti-CD3 preparations have reported preservation of B-cell function, with maintenance of higher endogenous insulin secretion assessed by C-peptide response and concomitant reduction in HbA1c and insulin usage in the treated group over at least a 1-year period of time [ 50– 50].
Noteworthy outcomes have been seen in two studies in new-onset type 1 diabetes using two different humanized anti-CD3, and both have reported preservation of β-cell function with maintenance of higher endogenous insulin secretion assessed by CPR and concomitant reduction in A1C levels and insulin usage in the treated group over at least 1 year (51, 52).
Positive correlation between over-accumulation of ethylene and a higher expression of Sl-PR1b in ABA-deficient mutant plants could indicate that maintenance of normal plant endogenous ABA content may be essential for the growth promoting action of B. megaterium by keeping low levels of ethylene production.
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maintenance of innate
maintenance of self
maintenance of reputational
maintenance of old
maintenance of didactic
maintenance of new
maintenance of historical
maintenance of genomic
maintenance of intra
maintenance of local
maintenance of domestic
maintenance of intrinsic
maintenance of indigenous
maintenance of spontaneous
maintenance of inner
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