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These findings raise the possibility that VEGF is required for the maintenance of distal neuronal processes in the adult animal, perhaps through promotion of remodelling of distal processes and synapses in the face of the demands of neuronal plasticity.
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In such cases, maintenance of the distal femoral condyles should be considered based on the ability to achieve adequate and appropriate muscular and superficial soft tissue coverage of the limb.
The maintenance of the distal articular block (femoral condyles) in this case is similar to what is done in some pediatric amputations to preserve length and prevent bony overgrowth [12].
PPARγ levels are directly regulated by Wnt molecules; therefore, changes in the Wnt microenvironment have close control over maintenance of the distal lung.
Thus, study of the 1 D extended model has demonstrated that cell growth and division in the root do not interfere with the formation and maintenance of the distal auxin maximum.
Open-ended perineurial sleeves provide distal continuity of the endoneurial microenvironment with the surrounding extracellular tissue space and may ensure maintenance of proximo-distal endoneurial fluid flow by providing distal drainage sites (see below).
Here we took a systematic approach to identify small molecules that support self-renewal of naive human ESCs based on maintenance of endogenous OCT4 distal enhancer activity, a molecular signature of ground state pluripotency.
This budding pattern is consistent with the maintenance of long term distal polarity landmarks proteins in quiescent yeast cells [16].
In the developing rat lung, mesenchymal FGF7 expression is required for the induction of branching morphogenesis of distal lung endoderm and the maintenance of an alveolar epithelial cell phenotype [5].
In T cells, ERM proteins are important for numerous functions including maintenance of microvilli, organization of proximal-distal T cell polarity, regulation of CD95-induced cell death, and promotion of TCR-induced signaling events leading to cytokine production [5] [13].
This facilitated maintenance of alignment between proximal, intermediate and distal bone segments.
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