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It functions as a scaffold for tissue morphogenesis, provides cues for cell proliferation and differentiation, promotes the maintenance of differentiated tissues and enhances the repair response after injury.
PPARγ is required for adipocyte differentiation and for the maintenance of differentiated adipocytes [65,66].
GATA3 is expressed in a variety of tissues, including the mammary gland, in which it is a key regulator of luminal cell lineage differentiation from mammary stem cells and maintenance of differentiated luminal epithelium within the mature gland [ 3, 4].
Daily lactate dehydrogenase activity measurements of the medium and immunofluorescence end-point staining proved the viability of the tissues and the maintenance of differentiated cellular phenotypes.
Cell cell communication and biochemical cross-talk have been shown to be essential for the maintenance of differentiated cell functions in tissues and organs.
Here we report two-dimensional cell sheet manipulation (2D CSM) of heterotypically co-cultured lung cell sheets and the maintenance of differentiated phenotypes of lung epithelial cells over prolonged periods of up to 70 days.
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Cell type- and tissue-specific expressions of cyclins and CKIs during development and in the adult are believed to not only underlie differences in cell cycling parameters but also to participate in promoting differentiation and/or maintenance of the differentiated state.
We sought to address the impact of telomere dysfunction not only upon the capacity for cell differentiation but also upon the maintenance of a differentiated state.
Furthermore, CCB treatment of whole embryos, even after neural crest cells have already migrated and differentiated, still causes a significant change in individual cell shape and morphogenic patterning, suggesting that maintenance of a differentiated state in neural crest cells may be regulated at least in part by -L-type channelschannels.
In contrast our previous and current studies indicate that Barx2 positively regulates the early steps of myoblast differentiation; however, its subsequent down-regulation may be necessary for maintenance of the differentiated state of myofibers.
Growth factors, in particular the TGF-b superfamily, influence many processes during cartilage formation, including cell proliferation, extracellular matrix synthesis, maintenance of the differentiated phenotype, and induction of MSCs towards chondrogenesis.
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maintenance of distinctive
maintenance of distinct
maintenance of disparate
maintenance of requirements
maintenance of divergent
maintenance of discrete
maintenance of heterogeneous
maintenance of segregated
maintenance of reputational
maintenance of old
maintenance of didactic
maintenance of historical
maintenance of new
maintenance of genomic
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