Sentence examples for maintenance of chromosomal from inspiring English sources

DNA methylation has many diverse functions in normal cells including silencing of transposable elements, inactivation of viral sequences, maintenance of chromosomal integrity, X-chromosome inactivation, and transcriptional suppression of a large number of genes [ 7, 8].

Telomeres are specialized nucleoprotein structures consisting of G-rich repetitive sequences that cap the ends of eukaryotic chromosomes and are crucial for the maintenance of chromosomal integrity and cell viability (McClintock et al 1941).

Telomeres are tandem repeats of the DNA sequence TTAGGG extending over 6 15 kb at the end of eukaryotic chromosomes, necessary for both successful DNA replication and maintenance of chromosomal integrity (8).

References 96 and 97 describe how the lincRNA Xist is divided into two repressive megadomains by the DXZ4 microsatellite region, which is required for maintenance of chromosomal architecture but, interestingly, not for Xist-mediated silencing activity.

Therefore, RAD17 links the checkpoint to ploidy control and is essential for the maintenance of chromosomal stability.

Using the RNA interference technique, we investigated the role of Rad9 in the genotoxic stress-induced activation of S-phase checkpoint and the maintenance of chromosomal stability.

Structural maintenance of chromosomes (SMC) proteins are evolutionarily conserved chromosomal proteins that are components of the cohesion complex, necessary for sister chromatid cohesion.

The original annotation and maintenance of the chromosomal sequences were provided by each chromosome sequencing group (Vassarotti et al. 1995), MIPS, and SGD.

Evidence from lower eukaryotes suggests that the chromosomal associations of all the structural maintenance of chromosome (SMC) complexes, cohesin, condensin and Smc5/6, are influenced by the Nipbl/Mau2 heterodimer.

Appropriate B-Myb expression is critical to the maintenance of chromosomally stable and pluripotent ES cells, but its absence promotes chromosomal instability that results in either aneuploidy or differentiation-associated cell death.

This would lead to the maintenance of large chromosomal fragments, as supported by the high conservation of linkage disequilibrium of peach.15 The consequences are that the parents used by breeders are often close relatives, with large regions of their genomes and those of the cultivars resulting from their offspring being identical by descent, as our results suggest.