Sentence examples for maintenance of checkpoints from inspiring English sources

The former entailed monitoring areas between HV and ARSK forward positions, verification that specific types of heavy weapons were at least 10 or away from the forward military positions or placed in storage, maintenance of checkpoints, chairing Joint Commissions, and performance of liaison functions.

BRCA1 participates in a number of cell functions that maintain genome integrity either directly through double strand break repair or indirectly through maintenance of checkpoints at G1, S and mitosis [ 20- 22].

We conclude that S92 phosphorylation is important for stable Cdc20Slp1-APC/C interactions and in particular for maintenance of checkpoint arrest.

Besides, CDC6 has a crucial role in the activation and maintenance of the checkpoints' mechanisms coordinating S phase and mitosis.

Given the improper maintenance of G2/M checkpoint in the CDK1 siRNA group, we went on to investigate mitotic progression using the mitosis-specific marker, phospho-Histone 3 (Ser10).

Overexpressed Bub3 evidently inhibited the homologous chromosome segregation, indicating that Bub3 is involved in monitoring the MI-AI transition, which is similar to a previous report firstly showing Xenopus Bub3 requirement for spindle checkpoint activation and for maintenance of the spindle checkpoint signal [50].

VE-822 decreased maintenance of cell-cycle checkpoints, increased persistent DNA damage and decreased homologous recombination in irradiated cancer cells.

Involvement in MT-binding and spindle checkpoint recruitment also appears to have been conserved from yeast to humans although hSPC105 is more prominent in both activities (e.g., recruitment versus maintenance of the spindle checkpoint).

To determine if RECQ1 is required for the maintenance of the G2/M checkpoint, cells were irradiated (10 Gy) and incubated in the presence of nocodazole for 16 h to capture cells entering mitosis.

In addition to their growth defects, RECQ1-depleted human cells display defective maintenance of the G2/M checkpoint following IR exposure and an aberrant apoptotic response to H2O2-induced stress.

Conversely, acute pharmacological inhibition of Cdk1 abrogates the engagement and maintenance of the mitotic checkpoint upon microtubule depolymerization.