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With its maintenance machinery thereby turned on high, each worm cell lives far longer — and so does the worm.
Tengzhong is known in China for making a wide range of road equipment, from bridge piers to highway construction and maintenance machinery.
The Manufacturing Operations segment engages in the design, research and development, production and sale of large track maintenance machinery as well as the manufacturing of components for railway construction.
Transporters, chaperones, and storage proteins constitute cellular Cu transport and maintenance machinery and are not part of the cuproproteome.
The biological function of copper is maintained by cuproproteomes, whereas the Cu transport and maintenance machinery serves an intermediate role and is not preserved during evolution when an organism lacks cuproproteins.
This provides insight into the mechanism of tumorigenesis and the manner in which glioma cells exploit the cellular telomere maintenance machinery.
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Reprogramming of cell proliferation and apoptosis and deregulation of genome integrity maintenance machineries are likely to underlie the association of EBV with a variety of malignancies, including virtually all cases of endemic Burkitt's lymphoma (BL) and nasopharyngeal carcinoma (NPC) and approximately half of Hodgkin's lymphomas (HL) [1], [4].
The second OB fold in turn contacts the related RMI2 factor (absent in yeast), together providing a docking site for other genome stability maintenance machineries [ 43, 44].
We have recently proposed that a prolonged "time for repair" could be a fundamental aspect in the soma maintenance machineries necessary to ensure longevity [ 8].
The nature and accuracy of these organelle-targeted DNA maintenance machineries can have a huge impact on organelle mutation rates (Sloan and Taylor 2012).
One explanation for the substitution rate patterns described here is that for a number of eukaryotes the fidelity and efficacy of mitochondrial maintenance machineries are more variable and capricious than those of plastids (Lynch et al. 2006; Richardson et al. 2013; Smith, Jackson, et al. 2014; Zhu et al. 2014).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com