However, further studies are needed to elucidate the function of complex I in brain development and maintenance of its function, especially the striatum and the basal ganglia.
However, the brain is not equipped to derive energy from fatty acids, but uninterrupted maintenance of its function is essential to organismal survival.
The immuno-privileged status of the testis is essential to the maintenance of its functions, and innate immunity is likely to play a key role in limiting harmful viral infections, as demonstrated in the rat.
Although LSD1 participates in several stages of HSC maintenance and differentiation, its function in complex with NuRD in hematopoiesis remains elusive [ 88].
The final stage of adipocytes differentiation requires the expression genes which are involved in the adipocytes phenotype and its function maintenance via lipid metabolic enzymes.
Survival is a more general term, considering only the implant is still in the oral cavity, without analyzing the quality of its function and maintenance of its support.
A clear understanding of the in vivo architecture of CENP-A chromatin is important, because it influences the molecular mechanisms of the assembly and maintenance of the centromere and its function in kinetochore nucleation.
BLM is known to interact with Topoisomerase IIIα (Topo III) and two other proteins with OB-fold domains, RMI1 and RMI2, to form a RTR complex (RecQ/Topo III/RMI) essential to maintenance of genome stability through its function in the resolution of recombination intermediates (for recent reviews see [22], [23]).
The splenic MZ is a complex environment in which a plethora of interactions among different cell types are required for its function and maintenance.
It is possible that the function of tankyrase 1 in mitosis (Dynek and Smith, 2004; Chang et al, 2005a) is less affected by PARP inhibitors than its function in maintenance of telomere length as mitosis is unaffected in PARP inhibitor-treated cells (Seimiya et al, 2005).
