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Demineralization and appearance of white spot lesions around brackets and bands have become a major concern during orthodontic treatment especially with the potential of these lesions to develop into caries when oral hygiene maintenance is compromised.
It is therefore relevant to examine how muscle maintenance is compromised by prolonged exposure to reduced gravitational forces.
If the activity of the Notch/PINK1/mTORC2/AKT signalling axis is reduced, neuroblast maintenance is compromised [ 101].
Another line of evidence indicates that stem and progenitor cells exhaustion can contribute substantially to the process of ageing, as determined by observations of stem and progenitor cells attrition in mouse models in which genome maintenance is compromised.
The utility of telomere length both as a biomarker for accelerated cellular replicative aging and as a diag-nostic marker for a constitutional defect in telomere maintenance solicits a question as to how telomere length varies in different tissues in conditions associated with accelerated cellular aging as compared to disorders where telomere length maintenance is compromised.
Similar(55)
In unilateral transtibial amputees maintenance of standing balance is compromised due to the lack of active ankle control in the prosthetic limb.
We demonstrate, here, that this advantage could be the maintenance of genome integrity, which is compromised when the dosage of these genes is reduced.
Furthermore, the lower number of HSCs in young Fancd2-deficient mice suggests that also the development or maintenance of these stem cells is compromised in the absence of an active FA pathway.
Genome maintenance is critical for cell viability and frequently is compromised in cancer.
First, they exert their effect only within a narrow therapeutic window in which their inhibitory effects on angiogenesis do not cause excessive toxicity; it has become apparent in recent years that normal blood vessels, and also the central nervous system, require VEGF-A for maintenance and are compromised when circulating VEGF-A falls below threshold levels (Carmeliet, 2003).
The maintenance BCG has been compromised because of serious side-effects (e.g., BCG sepsis and BCG-induced cystitis).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com