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Women were randomly assigned to receive an oxytocin maintenance infusion of 2.5 or 15 U/h.
Interventions: Amrinone, loading dose of 2 mg/kg, was administered before weaning from cardiopulmonary bypass, followed by a maintenance infusion of 7.5 μkg/kg/min.
28 healthy individuals underwent two MRI sessions within a timeframe of 2 weeks, each consisting of two structural T1-weighted MRIs within a single session, one before and one 45 min after infusion of S-ketamine (bolus of 0.11 mg/kg, followed by an maintenance infusion of 0.12 mg/kg) or placebo (0.9% NaCl infusion) using a crossover design.
In consequence, dexmedetomidine 1 mcg/kg was administered over 10 min as a loading dose then followed by a maintenance infusion of 0.7 mcg/kg/h.
With a maintenance infusion of <2000 IU/h, most circuits clotted.
After the randomization, a maintenance infusion of 5% glucose was started at the rate of 30 ml/kg per day.
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In the intensive care unit (ICU), she was awake while the maintenance infusion rate of dexmedetomidine was 0.35 mcg/kg/h.
Patients received a loading dose of dexmedetomidine (DEX) of 2.5 µg/kg/h over 10 min (approx 0.42 µg/kg) followed by a maintenance infusion rate of 0.7 µg/kg/h.
A rational fluid optimization protocol consisting of maintenance infusion covering basal loss and goal-directed top-ups has been proposed by other authors [ 6, 7].
Careful titration of the alfentanil maintenance infusion is recommended to minimize the possibility of postoperative respiratory depression.
Maintenance infusion was provided via administration of 0.25% levobupivacaine 0.1 mL/kg/h and fentanyl 2 μg/mL/h.
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