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Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk.
"Genetic variation in telomere maintenance genes in relation to ovarian cancer survival". International journal of molecular epidemiology and genetics 3 (3): 252.
About 35% of the Cell Growth and Maintenance genes in this set are annotated as ADR12, with another 8% annotated as the related gene ADR6.
In contrast, DNA methylation of selected genes was less variable but tended to be lower in inflammatory and higher in maintenance genes in EDTA/DTT released cells.
The most common annotation among the Cell Growth and Maintenance genes in PVSet2 (peak at the 400-500 mg stage) is ADR12, an auxin down-regulated gene of unknown function.
Although the genome maintenance genes in category L+ do have uptake sequence densities higher than average, they are not the highest ranked COG category in any species other than N. meningitidis.
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The subsequent identification of Brd4 as an important maintenance gene in acute myeloid leukemia (AML) fueled further interest in Brd4 as a cancer target (Zuber et al., 2011b).
The remarkably high natural genetic variation in maize should be ideally suited for mapping low-variance telomere-maintenance genes in mapping populations such as the recently developed NAM population (Gore et al. 2009; McMullen et al. 2009).
Consistent with HS effects on proteome maintenance genes, HS in wild-type mice increased the expression of genes involved in protein synthesis (HSA03010_RIBOSOME, RIBOSOMAL_PROTEINS, TRNA_SYNTHETASES) and degradation (HSA03050_PROTEASOME, PROTEASOME_DEGRADATION, PROTEASOMEPATHWAY, PROTEASOME) (Additional File 3).
(G ) Expression of core HSC maintenance genes increases in perinatal Nes-GFP+ BMSCs.
This list includes 535 housekeeping or maintenance genes expressed in 11 human adult and foetal tissues from [ 26], and 451 housekeeping or maintenance genes available at HugeIndex database [ 27].
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